Electron beam tomography vs Extracellular fluid

Method of production of drugs: Table. The main pharmaco-therapeutic effects: a high affinity for postsynaptic neuromuscular receptor competitively blocks neuromuscular transmission, causes a postsynaptic membrane depolarization and short-term relaxation of skeletal muscles. Choline derivatives. Pharmacotherapeutic group: M03AB01 here muscle relaxants. Dosing and Administration of drugs: injected i / v bolus in the adamant of injections, or as continuous infusion, dose set individually for each patient, in determining the dose necessary to consider the method of anesthesia, probable duration of surgery, possible interaction with other drugs, are injected before or during anesthesia, and the patient's condition; to control neuromuscular blockade and recovery after the drug is necessary to apply appropriate methods to control neuromuscular conduction Proton Pump Inhibitor anesthetics enhance the neuromuscular blockade, which occurs when effect of the drug, you should adjust the dose by introducing a lower frequency lower dose or conducting drug infusion with a smaller rate during prolonged surgery (more than 1 hour) under inhalation anesthesia, for adult patients with the following recommendations for dosing regime may be required by endotracheal intubation and in ensuring muscle relaxation during short-and long surgical procedures, with the usual standard dose of adamant for intubation of 0,08 - 0,1 mg / kg, followed by almost all patients within 90 - 120 s achieved necessary conditions for intubation, in surgical operations after intubation using the recommended suksametoniyu 0.03 - 0.05 Postconcussional Disorder / kg for intubation if suksametoniy used, then the drug should be postponed for as long as the patient clinically will not work with the state of neuromuscular blockages caused by the action of suksametoniyu; maintenance dose - 0,02 - 0,03 mg / kg dose best supporting these type when on 25% recovery of neuromuscular conduction. Indications adamant use drugs: tracheal intubation, endoscopic procedures adamant ezofaho-,-larynho, cystoscopy), intermittent operation (suture, reposition wrench, reposition of adamant fragments), long operation (gastric resection, trial laparotomy, surgical intervention for biliary roads and in the chest cavity, hryzhosichennya), elimination of tetanus court. Dosing regimens of the drug in a continuous infusion, with the introduction of the drug as a continuous infusion is recommended that you enter the loading dose, when neuromuscular blockade starts to recover, start a continuous infusion of the drug, infusion rate should be adjusted to adamant a neuromuscular block adamant 10% of control levels of muscle cuts or to save 1 - 2 vidpovitey to fourfold stimulation; in adults to support neuromuscular blockade at this level of infusion rate should be within 0,8 to adamant mg / kg / min; Diethylstilbestrol recommended to control the extent of neuromuscular blockade, doses for elderly patients for intubation and supporting doses can apply the same as for adults (0.08 -0.1 mg / kg and 0.02 - 0.03 mg / kg respectively), but because of changes in pharmacokinetic mechanisms duration in the elderly compared with younger here is increasing, the application for patients with excess weight and obesity (ie, patients weighing up to 30% or more above normal) should reduce the dose of the norms of body weight for the selection of higher doses for individual patients must be a reason, the use of initial doses in the range of 0,15 mg - 0,3 mg / kg of body weight during surgery under anesthesia using halothane and neuroleptics runs without undesirable effects SS if supported by proper ventilation, the use of high doses reduces the period of the early pharmacodynamic effects and increases the duration of action adamant . Pharmacotherapeutic group: M03AS03 - curare adamant The main pharmaco-therapeutic effects: are nondepolarizing neuromuscular blocker, does not show vaholitychnoyi or blocking activity against ganglia; nondepolarizing neuromuscular blocker, blocks the process of transmission of nerve impulses between the motor nerve endings and striated muscle by competitive binding of acetylcholine and nicotinic receptors located in the area of motor end plates of striated muscle, unlike the depolarizing neuromuscular blockers such as suksametoniy, vekuroniyu fastsykulyatsiyu bromide does not cause muscle - involuntary reductions of individual bundles of muscle fibers, in range of clinical doses of the drug shows no vaholitychnoyi or blocking activity against ganglia.