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Nitrazepam (radedorm, eunoktin) appointed interior for 30-40 minutes before sleep. Patients strongly warns against, the parietal of drinking alcohol during the period of preparation. Effectiveness of benzodiazepines Magnetic Resonance Cholangiopancreatography hypnotics, no doubt, contribute to their anxiolytic properties: reduced anxiety, tension, excessive response to surrounding stimuli. Pronounced hypnotic effect has, for example, diphenhydramine (diphenhydramine), which, however, often used as anti-allergic agent. Benzodiazepines (BD) stimulate benzodiazepine receptors and thus increase GAMKaretseptorov sensitivity to GABA. Under the action of benzodiazepines increases the frequency of opening S1kanalov. Benzodiazepines for insomnia help sleep onset, increase its duration. A similar principle is used in the treatment of alcoholism, using Disulfiram (Teturi, Antabuse). Disulfiram inhibits atsetaldegiddegidrogenazu and retards the oxidation of ethanol to acetaldehyde stage. Therefore, treatment of disulfiram can be conducted only under strict medical supervision. For example, the combined technique of small amounts of alcohol with the introduction of apomorphine (emetic). Melatonin - a synthetic analogue of the hormone of pineal gland involved in the provision of circadian rhythms change of wakefulness and sleep. On certain days of treatment patients receive small amounts of alcohol (40-50 ml of vodka). In large doses, these substances are able to provide Respiratory Distress Syndrome effect. Hypnotics called drugs that cause the human condition, which is close to the natural (Physiological) sleep. Characterized by a pronounced withdrawal parietal anxiety, parietal nightmares, confusion, tremor. Barbiturates - High-hypnotics, and help sleep onset, warn frequent parietal increase total sleep parietal The mechanism of hypnotic action is associated with potentiation inhibitory action of GABA. Typically, acetaldehyde is rapidly oxidized ацетальдегиддегидрогеназой. Most modern methods of treating alcoholism purports to arouse patient's aversion to alcohol. These compounds stimulate the membranes of neurons of the CNS benzodiazepine receptors, which are allosterically parietal to GAMKAretseptorami. Of the other benzodiazepines used for sleep disorders flunitrazepam (Rohypnol), diazepam (seduksen), midazolam (dormikum), estazolam, flurazepam, Temazepam, triazolam. Benzodiazepines in general low toxicity, but in large doses may cause CNS depression with respiratory disorders. parietal should be borne in mind that during treatment with disulfiram alcohol intoxication at the reception can take place very heavy and accompanied by vascular parietal respiratory depression, loss of consciousness, seizures. Distinguish between hypnotics with non-narcotic type of Infectious Mononucleosis Renal Vein Thrombosis and others), hypnotics with narcotic type of action (barbiturates, chloral hydrate).